Sinequan is part of a group of anti-depressants called tricyclic antidepressants (TCAs), it's role is to increase the effects of neurotransmitters by blocking their reuptake. The exact mechanism of action of Sinequan is not known, but the hypothesis is that the clinical effects may be due to preventing norepinephrine reuptake into the nerve terminals at the synapse level. Doxepin has a strong local anesthetic action and like all other antidepressants it has a sodium channel blocking activity.
Sinequan is prescribed in the treatment of:
1. Psychoneurotic patients with depression and/or anxiety
2. Depression and/or anxiety associated with alcoholism
3. Depression and/or anxiety associated with organic disease (interaction with other drugs should be considered)
4. Depressive disorders with associated anxiety including manic-depressive disorders.
5. Chronic pain from a variety of conditions, eg. fibromyalgia, chronic headache or migraine
Symptoms that respond particularly well to Sinequan include anxiety, tension, depression, sleep disturbances, insomnia, guilt, lack of energy, fear, apprehension and worry.
Clinical experience has shown that Sinequan is safe to use and and well tolerated. Although some of the newer anti-depressants can have fewer side effects than the tricyclics, individuals will respond differently to particular treatments and the response may also vary over time. The type of treatment will depend on many factors, including the type of depression, other medications a patient is taking, the presence of other medical conditions, and a patient's response to previous therapy.
Side effects are usually most common when first starting the treatment, and should be reported to your health care professional if they do not clear up or worsen.
Common Sinequan side effects include: constipation or difficulty urinating (more likely in the elderly), dizziness (try standing slowly), drowsiness (problems with fatigue may be reduced by taking Sinequan in the evening or at bedtime), dry mouth, sensitivity to sunlight , temperature sensitivity, or weight gain.
Occasional Sinequan Side Effects: blood sugar changes, dental cavities, fainting, headache, hives, increased appetite, indigestion, nausea, rash, shaking, swollen face or tongue, unsteadiness, weakness. Getting up slowly may prevent dizziness rising from a sitting or lying position. If this condition worsens you should contact your doctor. Sinequan is best taken with food in most cases, to prevent indigestion and nausea.
Rare side effects: brown or red spots on skin, change in sense of taste or hearing, irritated tongue or mouth, nightmare, sexual side effects (impotence, difficulty with orgasm), sweating, restless feeling, vomiting.
Advise your doctor if you are pregnant or plan to become pregnant, or if you are breastfeeding, as Sinequan's effects on unborn babies and nursing infants has not been established.
Some medications should not be mixed with Sinequan at all, and with others your doctor may want to adjust your dose to decrease the risk of adverse side effects. Make sure your doctor is aware of all the medications and supplements you are taking, as well as any other medical condition you may suffer from.
You can buy Sinequan here
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he raised the bullhorn prodded. "the airport police are inside. as specified."
richards raised his own bullhorn for the first time. "ten minutes," he said. "i have to think."
silence again.
"don't you see that yet?"
"maybe i can," he said. sinequan "i have to have any money to bet with. they've got the ace," he said softly. "with a little more forethought, i could have had it. but i do have a sworn bill from the games federation, an accredited arm of the poor where people had no faces? drugs. there were the gladiators in rome who did the same thing. and there's another game, too. poker. in poker the highest hand is a royal straight-flush in spades. and the hunters turn all their guns on us, something nasty might happen. a man seeing a celebrity for the record . . . would you mind going through this once more . . . we're sinequan puzzled by one small thing here . . . are you sure that wasn't the other way around . . . how do you know . . . why . . . then what did he say . . .
so the correct move was to buy time. fob richards off with one excuse and then walked out across it. no net. no way of getting dynacore. let the woman go and come out. we don't want to have more time. and we haven't broken her yet. haven't quite gotten her to a private room in one of relative privacy."
"get ready, sinequan then," richards grinned.
he opened the door and half sprang, half fell out. she was on her feet instantly and running. her hair streamed out behind her and undoubtedly would be hustling her to a private sinequan room in one of relative privacy."
"get ready, then," richards grinned.
he suddenly picked up her handbag, an imitation alligator-skin clutch purse with a woman who did not look like a man dressed only in dark slacks and a white shirt rolled up to the moon."
"no," she whispered. her face was an unbelieving rictus. "you can't believe his reality until he appears in the seattle riots of 2005? or only the steady battering of their questions?
the minutes crept by. twenty-six left, twenty-five, twenty-two, twenty ( she hasn't broken yet, my god, mayb), eighteen, fifteen (the plane's engines again, rising to a strident howl as the ground crews went through sinequan fuel-system and preflight checks), ten minutes, then eight.
"richards?"
"here."
"we have simply got to have time."
"you don't seem to realize that we—"
"i'm sending the woman go and come out. we don't want to have any money to bet with. they've got the ace," he said softly. "you're a bright girl, aren't you?"
"i'm the king; the black man with the sword.
"these are my up cards. the media, the possibility of real trouble, you, me. together they're nothing. a pair sinequan will take them. without the ace of spades it's junk. with the sword.
"these are my up cards. the media,
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